Product Description
FOXO4-DRI Peptide Overview
FOXO4-DRI is a synthetic D-retro-inverso (DRI) peptide engineered to disrupt the interaction between FOXO4 and p53, a critical pathway involved in the survival of senescent cells. This research-grade peptide is widely utilized in in vitro cellular senescence studies to investigate mechanisms of selective apoptosis in senescent cell populations.
By interfering with FOXO4-mediated nuclear retention of p53, FOXO4-DRI promotes p53-dependent apoptotic signaling, enabling detailed examination of senescence-associated cellular pathways. The peptide has been referenced in preclinical research models, including aged murine systems, for its role in elucidating age-related cellular dysfunction.
Research Applications
FOXO4-DRI is supplied as a lyophilized peptide and is intended exclusively for qualified laboratory research use. It serves as a valuable molecular tool for studying:
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Cellular senescence and senescence-associated pathways
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p53-mediated apoptotic mechanisms
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Senolytic screening and pathway validation
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Chemotoxicity and cellular stress response modeling in vitro
Product Quality and Assurance
Each batch of FOXO4-DRI undergoes independent third-party analytical testing to verify molecular identity, purity, sterility, and endotoxin levels. Limitless Biotech maintains rigorous quality control standards through controlled manufacturing and validation protocols to ensure consistency and reliability for research applications.
Supply and Manufacturing
SynoPept supplies USA-manufactured FOXO4-DRI peptide with verified amino acid sequence integrity and documented analytical results. Products are packaged to preserve stability and shipped promptly, supported by dedicated scientific customer service.
For research use only. Not intended for diagnostic, therapeutic, or clinical use.
