Actin-Regulatory Peptide Overview
TB-500X is a synthetic analog of Thymosin Beta-4, a 43–amino acid peptide originally identified in thymic tissue. This research-grade peptide is widely utilized in in vitro studies focused on cytoskeletal regulation, particularly actin-binding dynamics that influence cell motility and structural remodeling.
Cellular Migration & Regeneration Research
In laboratory models, Thymosin Beta-4 is examined for its role in cell migration, differentiation, and tissue regeneration pathways. Research applications explore mechanisms related to wound response, angiogenic signaling, and cellular organization within regenerative biology frameworks.
Vascular & Tissue Engineering Applications
Experimental studies investigate TB-500X in contexts such as neovascularization, extracellular matrix interactions, and anti-inflammatory signaling. Additional in vitro research areas include tissue engineering models, hair follicle biology, and neural regeneration pathway exploration.
Laboratory Performance & Stability
Supplied as a white lyophilized powder, TB500X demonstrates reliable stability under recommended storage conditions and reconstitutes efficiently in sterile water. Its molecular consistency supports reproducible outcomes in extended experimental protocols.
Pharmaceutical-Grade Manufacturing by SynoPept
Manufactured in the United States by SynoPept under GMP-compliant, pharmaceutical-grade standards, each batch undergoes independent third-party testing. Quality control includes verification of molecular identity, purity, sterility, and endotoxin levels to meet rigorous research requirements.
Analytical Specifications
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Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
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Molecular Formula: C212H350N56O78S
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Molecular Weight: 4963.55 g/mol
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CAS Number: 77591-33-4
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PubChem CID: 16132341
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Synonyms: Thymosin Beta-4, Tβ4, TB-500, Timbetasin
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Purity: ≥99% (HPLC)
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Form: White lyophilized powder
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Solubility: Sterile water
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Storage: −20°C, tightly sealed, protected from heat and moisture
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Shelf Life: 24 months when stored properly
Research-Only Classification
TB500X is supplied strictly for in vitro research use only (RUO). It is not intended for human or animal consumption, diagnostic use, or therapeutic application.


